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1 From the Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Bethesda, Md. Received May 19, 2000; revision requested June 16; revision received January 22, 2001; accepted February 6.
A 47-year-old woman presented with a 5-year history of intermittent episodes of excruciating back pain confined to the sacral area. There was no radiation of pain, but the right leg occasionally "gave way." The back pain usually resolved spontaneously with rest. Recently, she complained of urinary incontinence.
Findings at physical examination were as follows: joint laxity, bilateral iridodonesis, and decreased vibration sensation of the toes. During the course of her work-up, magnetic resonance (MR) imaging (Figs 1, 2), echocardiography (Fig 3), and slitlamp examination of the eye (Fig 4) were performed.
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Figure 1. Sagittal T1-weighted spin-echo MR image (416/8 [repetition time msec/echo time msec]) of the spine.
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Figure 2. Transverse T2-weighted fast spin-echo MR image (3,000/96).
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Figure 3a. (a) Longitudinal two-dimensional echocardiogram. (b) M-mode echocardiogram.
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Figure 3b. (a) Longitudinal two-dimensional echocardiogram. (b) M-mode echocardiogram.
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Figure 4. Image shows findings of slitlamp examination of the eye.
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《放射学杂志》2003年2月第226卷第2期
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