Finally, the antibiogram of CA-MRSA isolates may vary from country to country. In Taiwan, CA-MRSA isolates are also resistant to multiple antimicrobial agents; 71.4%, 91.4%, and 41.2% are resistant to clindamycin, erythromycin, and chloramphenicol, respectively (4). Trimethoprim/sulfamethoxazole is more effective against CA-MRSA isolates than other first-line antimicrobial agents: the resistance rate is 0%–65.7% (4,5). Therefore, clindamycin and trimethoprim/sulfamethoxazole may be not adequate empiric antimicrobial agents for SSTIs in Taiwan or other areas with a high prevalence of CA-MRSA.

    Jui-Shan Ma

    Show-Chwan Memorial Hospital, Changhua, Taiwan

    Ma J-S. Methicillin-resistant Staphylococcus aureus skin infections [letter]. Emerg Infect Dis [serial on the Internet]. 2005 Oct [date cited]. Available from http://www.cdc.gov/ncidod/EID/vol11no10/05-0680_05-0858.htm

    References

    Moran GJ, Amii RN, Abrahamian FM, Talan DA. Methicillin-resistant Staphylococcus aureus in community-acquired skin infections. Emerg Infect Dis. 2005;11:928–30.

    Lee MC, Rios AM, Aten MF, Mejias A, Cavuoti D, McCracken GH Jr, et al. Management and outcome of children with skin and soft tissue abscesses caused by community-acquired methicillin-resistant Staphylococcus aureus. Pediatr Infect Dis J. 2004;23:123–7.

    Chen CJ, Huang YC, Chiu CH, Su LH, Lin TY. Clinical features and genotyping analysis of community-acquired methicillin-resistant Staphylococcus aureus infections in Taiwanese children. Pediatr Infect Dis J. 2005;24:40–5.

    Wang CC, Lo WT, Chu ML, Siu LK. Epidemiological typing of community-acquired methicillin-resistant Staphylococcus aureus isolates from children in Taiwan. Clin Infect Dis. 2004;39:481–7.

    Fang YH, Hsueh PR, Hu JJ, Lee PI, Chen JM, Lee CY, et al. Community-acquired methicillin-resistant Staphylococcus aureus in children in northern Taiwan. J Microbiol Immunol Infect. 2004;37:29–34.

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《传染病的形成》2005年10月第11卷第10期